2,6-Dimethoxybenzoic acid
- Product Name
- 2,6-Dimethoxybenzoic acid
- CAS No.
- 1466-76-8
- Chemical Name
- 2,6-Dimethoxybenzoic acid
- Synonyms
- AKOS BBS-00003742;RARECHEM AL BO 1076;2,6-Dimethoxybenzoic;Novobiocin Impurity 4;2,6-dimethoxy-benzoicaci;2,6-DIMETHOXYBENZOIC ACID;Benzoicacid,2,6-dimethoxy-;2,6-DimethoxybenzoicAcid>2,6-Dimethoxybenzoic acid,99%;γ-Resorcylic acid diMethyl ether
- CBNumber
- CB0303008
- Molecular Formula
- C9H10O4
- Formula Weight
- 182.17
- MOL File
- 1466-76-8.mol
2,6-Dimethoxybenzoic acid Property
- Melting point:
- 185-187 °C (lit.)
- Boiling point:
- 275.56°C (rough estimate)
- Density
- 1.2481 (rough estimate)
- refractive index
- 1.4500 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 14.7g/l soluble
- form
- Crystalline Powder
- pka
- pK1:3.44 (25°C)
- color
- White to off-white
- Water Solubility
- 0.35 g/100 mL (25 ºC)
- BRN
- 2212190
- InChIKey
- MBIZFBDREVRUHY-UHFFFAOYSA-N
- LogP
- 0.660
- CAS DataBase Reference
- 1466-76-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 2,6-dimethoxy-(1466-76-8)
- EPA Substance Registry System
- Benzoic acid, 2,6-dimethoxy- (1466-76-8)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- DG8598725
- TSCA
- Yes
- HS Code
- 29189010
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D131601
- Product name
- 2,6-Dimethoxybenzoic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $66.9
- Updated
- 2023/06/20
- Product number
- D1959
- Product name
- 2,6-Dimethoxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $54
- Updated
- 2024/03/01
- Product number
- D1959
- Product name
- 2,6-Dimethoxybenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 250g
- Price
- $399
- Updated
- 2023/06/20
- Product number
- A14418
- Product name
- 2,6-Dimethoxybenzoic acid, 99%
- Packaging
- 25g
- Price
- $40.6
- Updated
- 2024/03/01
- Product number
- A14418
- Product name
- 2,6-Dimethoxybenzoic acid, 99%
- Packaging
- 100g
- Price
- $104
- Updated
- 2024/03/01
2,6-Dimethoxybenzoic acid Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder. Hardly soluble in water, soluble in alkali and organic solvents, such as benzene and toluene.
Uses
2,6-Dimethoxybenzoic Acid is used in the synthesis of indoles as well as coumarins related to Novobiocin (N888500), used as potent inhibitors of heat-shock protein 90 in the treatment of breast cancer.
Preparation
2,6-Dimethoxybenzoic acid is the key intermediate in the preparation of gamma-resorcylic acid which has been described as having activity against rheumatic fever.
The Preparation of 2,6-Dimethoxybenzoic Acid
Cite this: J. Org. Chem. 1956, 21, 3, 368–369
Publication Date:March 1, 1956
https://doi.org/10.1021/jo01109a604
Definition
ChEBI: 2,6-Dimethoxybenzoic acid is a member of benzenes and a carbonyl compound. It is a polyphenol compound found in foods of plant origin.
Synthesis Reference(s)
Synthetic Communications, 22, p. 13, 1992 DOI: 10.1080/00397919208021074
Flammability and Explosibility
Not classified
Purification Methods
Crystallise the acid from water or 1,1-dichloroethane (m 187.5-188.5o). [Beilstein 10 H 388, 10 I 185, 10 II 259, 10 III 1401, 10 IV 1456.]
2,6-Dimethoxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Dimethoxybenzoic acid Suppliers
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View Lastest Price from 2,6-Dimethoxybenzoic acid manufacturers
- Product
- 2,6-Dimethoxybenzoic acid 1466-76-8
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000 Ton
- Release date
- 2023-03-21
- Product
- 2,6-Dimethoxybenzoic acid 1466-76-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-30
- Product
- 2,6-Dimethoxybenzoic acid 1466-76-8
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2023-06-06